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Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks

Transmission of influenza A viruses (IAV) between hosts is subject to numerous physical and biological barriers that impose genetic bottlenecks, constraining viral diversity and adaptation. The bottlenecks within hosts and their potential impacts on evolutionary pathways taken during infection are p...

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Detalles Bibliográficos
Autores principales: Amato, Katherine A., Haddock, Luis A., Braun, Katarina M., Meliopoulos, Victoria, Livingston, Brandi, Honce, Rebekah, Schaack, Grace A., Boehm, Emma, Higgins, Christina A., Barry, Gabrielle L., Koelle, Katia, Schultz-Cherry, Stacey, Friedrich, Thomas C., Mehle, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197827/
https://www.ncbi.nlm.nih.gov/pubmed/35701424
http://dx.doi.org/10.1038/s41467-022-31147-0