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Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks
Transmission of influenza A viruses (IAV) between hosts is subject to numerous physical and biological barriers that impose genetic bottlenecks, constraining viral diversity and adaptation. The bottlenecks within hosts and their potential impacts on evolutionary pathways taken during infection are p...
Autores principales: | Amato, Katherine A., Haddock, Luis A., Braun, Katarina M., Meliopoulos, Victoria, Livingston, Brandi, Honce, Rebekah, Schaack, Grace A., Boehm, Emma, Higgins, Christina A., Barry, Gabrielle L., Koelle, Katia, Schultz-Cherry, Stacey, Friedrich, Thomas C., Mehle, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197827/ https://www.ncbi.nlm.nih.gov/pubmed/35701424 http://dx.doi.org/10.1038/s41467-022-31147-0 |
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