Deletion in chromosome 6 spanning alpha-synuclein and multimerin1 loci in the Rab27a/b double knockout mouse

We report an incidental 358.5 kb deletion spanning the region encoding for alpha-synuclein (αsyn) and multimerin1 (Mmrn1) in the Rab27a/Rab27b double knockout (DKO) mouse line previously developed by Tolmachova and colleagues in 2007. Western blot and RT-PCR studies revealed lack of αsyn expression...

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Detalles Bibliográficos
Autores principales: Pattanayak, Rudradip, Underwood, Rachel, Crowley, Michael R., Crossman, David K., Morgan, Jennifer R., Yacoubian, Talene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197848/
https://www.ncbi.nlm.nih.gov/pubmed/35701443
http://dx.doi.org/10.1038/s41598-022-13557-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197848/
https://www.ncbi.nlm.nih.gov/pubmed/35701443
http://dx.doi.org/10.1038/s41598-022-13557-8

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