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Cas9-induced large deletions and small indels are controlled in a convergent fashion
Repair of Cas9-induced double-stranded breaks results primarily in formation of small insertions and deletions (indels), but can also cause potentially harmful large deletions. While mechanisms leading to the creation of small indels are relatively well understood, very little is known about the ori...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197861/ https://www.ncbi.nlm.nih.gov/pubmed/35701408 http://dx.doi.org/10.1038/s41467-022-30480-8 |