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Biological Equivalence of GGTA-1 Glycosyltransferase Knockout and Standard Porcine Pericardial Tissue Using 90-Day Mitral Valve Implantation in Adolescent Sheep

OBJECTIVE: There is growing interest in the application of genetically engineered reduced antigenicity animal tissue for manufacture of bioprosthetic heart valves (BHVs) to reduce antibody induced tissue calcification and accelerated structural valve degeneration (SVD). This study tested biological...

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Detalles Bibliográficos
Autores principales: McGregor, Christopher, Salmonsmith, Jacob, Burriesci, Gaetano, Byrne, Guerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197892/
https://www.ncbi.nlm.nih.gov/pubmed/34820778
http://dx.doi.org/10.1007/s13239-021-00585-0