Development of a Spray-Dried Formulation of Peptide-DNA Nanoparticles into a Dry Powder for Pulmonary Delivery Using Factorial Design

BACKGROUND: Gene therapy via pulmonary delivery holds the potential to treat various lung pathologies. To date, spray drying has been the most promising method to produce inhalable powders. The present study determined the parameters required to spray dry nanoparticles (NPs) that contain the deliver...

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Detalles Bibliográficos
Autores principales: Munir, Miftakul, Kett, Vicky L., Dunne, Nicholas J., McCarthy, Helen O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197895/
https://www.ncbi.nlm.nih.gov/pubmed/35441318
http://dx.doi.org/10.1007/s11095-022-03256-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197895/
https://www.ncbi.nlm.nih.gov/pubmed/35441318
http://dx.doi.org/10.1007/s11095-022-03256-4

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