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Development of a Spray-Dried Formulation of Peptide-DNA Nanoparticles into a Dry Powder for Pulmonary Delivery Using Factorial Design
BACKGROUND: Gene therapy via pulmonary delivery holds the potential to treat various lung pathologies. To date, spray drying has been the most promising method to produce inhalable powders. The present study determined the parameters required to spray dry nanoparticles (NPs) that contain the deliver...
Autores principales: | Munir, Miftakul, Kett, Vicky L., Dunne, Nicholas J., McCarthy, Helen O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197895/ https://www.ncbi.nlm.nih.gov/pubmed/35441318 http://dx.doi.org/10.1007/s11095-022-03256-4 |
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