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Anti-inflammatory Effects of Novel P2X4 Receptor Antagonists, NC-2600 and NP-1815-PX, in a Murine Model of Colitis

The pharmacological blockade of P2X4 receptors has shown potential benefits in the management of several immune/inflammatory diseases. However, data regarding the involvement of P2X4 receptors in the pathophysiological mechanisms of action in intestinal inflammation are not well defined. We aimed to...

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Detalles Bibliográficos
Autores principales: D’Antongiovanni, Vanessa, Pellegrini, Carolina, Benvenuti, Laura, Fornai, Matteo, Di Salvo, Clelia, Natale, Gianfranco, Ryskalin, Larisa, Bertani, Lorenzo, Lucarini, Elena, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Nemeth, Zoltan H., Haskó, György, Antonioli, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197920/
https://www.ncbi.nlm.nih.gov/pubmed/35338432
http://dx.doi.org/10.1007/s10753-022-01663-8