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Prognostic significance of RNA-based TP53 pathway function among estrogen receptor positive and negative breast cancer cases

TP53 and estrogen receptor (ER) are essential in breast cancer development and progression, but TP53 status (by DNA sequencing or protein expression) has been inconsistently associated with survival. We evaluated whether RNA-based TP53 classifiers are related to survival. Participants included 3213...

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Detalles Bibliográficos
Autores principales: Hurson, Amber N., Abubakar, Mustapha, Hamilton, Alina M., Conway, Kathleen, Hoadley, Katherine A., Love, Michael I., Olshan, Andrew F., Perou, Charles M., Garcia-Closas, Montserrat, Troester, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198049/
https://www.ncbi.nlm.nih.gov/pubmed/35701440
http://dx.doi.org/10.1038/s41523-022-00437-7