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ID proteins promote the survival and primed-to-naive transition of human embryonic stem cells through TCF3-mediated transcription

Inhibition of DNA binding proteins 1 and 3 (ID1 and ID3) are important downstream targets of BMP signalling that are necessary for embryonic development. However, their specific roles in regulating the pluripotency of human embryonic stem cells (hESCs) remain unclear. Here, we examined the roles of...

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Detalles Bibliográficos
Autores principales: Jiang, Haibin, Du, Mingxia, Li, Yaning, Zhou, Tengfei, Lei, Jia, Liang, Hongqing, Zhong, Zhen, Al-Lamki, Rafia S., Jiang, Ming, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198052/
https://www.ncbi.nlm.nih.gov/pubmed/35701409
http://dx.doi.org/10.1038/s41419-022-04958-8