The human “contaminome”: bacterial, viral, and computational contamination in whole genome sequences from 1000 families

The unmapped readspace of whole genome sequencing data tends to be large but is often ignored. We posit that it contains valuable signals of both human infection and contamination. Using unmapped and poorly aligned reads from whole genome sequences (WGS) of over 1000 families and nearly 5000 individ...

Descripción completa

Detalles Bibliográficos
Autores principales: Chrisman, Brianna, He, Chloe, Jung, Jae-Yoon, Stockham, Nate, Paskov, Kelley, Washington, Peter, Wall, Dennis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198055/
https://www.ncbi.nlm.nih.gov/pubmed/35701436
http://dx.doi.org/10.1038/s41598-022-13269-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198055/
https://www.ncbi.nlm.nih.gov/pubmed/35701436
http://dx.doi.org/10.1038/s41598-022-13269-z

Ejemplares similares