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The human “contaminome”: bacterial, viral, and computational contamination in whole genome sequences from 1000 families
The unmapped readspace of whole genome sequencing data tends to be large but is often ignored. We posit that it contains valuable signals of both human infection and contamination. Using unmapped and poorly aligned reads from whole genome sequences (WGS) of over 1000 families and nearly 5000 individ...
Autores principales: | Chrisman, Brianna, He, Chloe, Jung, Jae-Yoon, Stockham, Nate, Paskov, Kelley, Washington, Peter, Wall, Dennis P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198055/ https://www.ncbi.nlm.nih.gov/pubmed/35701436 http://dx.doi.org/10.1038/s41598-022-13269-z |
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