Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation

α-Synuclein (αSyn) is a small disordered protein, highly conserved in vertebrates and involved in the pathogenesis of Parkinson’s disease (PD). Indeed, αSyn amyloid aggregates are present in the brain of patients with PD. Although the pathogenic role of αSyn is widely accepted, the physiological fun...

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Detalles Bibliográficos
Autores principales: Acquasaliente, Laura, Pontarollo, Giulia, Radu, Claudia Maria, Peterle, Daniele, Artusi, Ilaria, Pagotto, Anna, Uliana, Federico, Negro, Alessandro, Simioni, Paolo, De Filippis, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198058/
https://www.ncbi.nlm.nih.gov/pubmed/35701444
http://dx.doi.org/10.1038/s41598-022-12886-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198058/
https://www.ncbi.nlm.nih.gov/pubmed/35701444
http://dx.doi.org/10.1038/s41598-022-12886-y

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