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Thermostable H1 hemagglutinin stem with M2e epitopes provides broad cross-protection against group1 and 2 influenza A viruses

Hemagglutinin (HA) stem-based vaccines have limitations in providing broad and effective protection against cross-group influenza viruses, despite being a promising universal vaccine target. To overcome the limited cross-protection and low efficacy by HA stem vaccination, we genetically engineered a...

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Detalles Bibliográficos
Autores principales: Subbbiah, Jeeva, Oh, Judy, Kim, Ki-Hye, Shin, Chong Hyun, Park, Bo Ryoung, Bhatnagar, Noopur, Jung, Yu-Jin, Lee, Youri, Wang, Bao-Zhong, Seong, Baik-Lin, Kang, Sang-Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198381/
https://www.ncbi.nlm.nih.gov/pubmed/35755946
http://dx.doi.org/10.1016/j.omtm.2022.05.007