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Thermostable H1 hemagglutinin stem with M2e epitopes provides broad cross-protection against group1 and 2 influenza A viruses
Hemagglutinin (HA) stem-based vaccines have limitations in providing broad and effective protection against cross-group influenza viruses, despite being a promising universal vaccine target. To overcome the limited cross-protection and low efficacy by HA stem vaccination, we genetically engineered a...
Autores principales: | Subbbiah, Jeeva, Oh, Judy, Kim, Ki-Hye, Shin, Chong Hyun, Park, Bo Ryoung, Bhatnagar, Noopur, Jung, Yu-Jin, Lee, Youri, Wang, Bao-Zhong, Seong, Baik-Lin, Kang, Sang-Moo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198381/ https://www.ncbi.nlm.nih.gov/pubmed/35755946 http://dx.doi.org/10.1016/j.omtm.2022.05.007 |
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