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Ribosomal RNA Pseudouridylation: Will Newly Available Methods Finally Define the Contribution of This Modification to Human Ribosome Plasticity?

In human rRNA, at least 104 specific uridine residues are modified to pseudouridine. Many of these pseudouridylation sites are located within functionally important ribosomal domains and can influence ribosomal functional features. Until recently, available methods failed to reliably quantify the le...

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Detalles Bibliográficos
Autores principales: Barozzi, Chiara, Zacchini, Federico, Asghar, Sidra, Montanaro, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198423/
https://www.ncbi.nlm.nih.gov/pubmed/35719370
http://dx.doi.org/10.3389/fgene.2022.920987