ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels

Ataxia-telangiectasia mutated (ATM) is one of the three main apical kinases at the crux of DNA damage response and repair in mammalian cells. ATM activates a cascade of downstream effector proteins to regulate DNA repair and cell cycle checkpoints in response to DNA double-strand breaks. While ATM i...

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Detalles Bibliográficos
Autores principales: Shah, Pragya, McGuigan, Connor W., Cheng, Svea, Vanpouille-Box, Claire, Demaria, Sandra, Weiss, Robert S., Lammerding, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198445/
https://www.ncbi.nlm.nih.gov/pubmed/35721517
http://dx.doi.org/10.3389/fcell.2022.875132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198445/
https://www.ncbi.nlm.nih.gov/pubmed/35721517
http://dx.doi.org/10.3389/fcell.2022.875132

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