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ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels

Ataxia-telangiectasia mutated (ATM) is one of the three main apical kinases at the crux of DNA damage response and repair in mammalian cells. ATM activates a cascade of downstream effector proteins to regulate DNA repair and cell cycle checkpoints in response to DNA double-strand breaks. While ATM i...

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Detalles Bibliográficos
Autores principales:	Shah, Pragya, McGuigan, Connor W., Cheng, Svea, Vanpouille-Box, Claire, Demaria, Sandra, Weiss, Robert S., Lammerding, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198445/ https://www.ncbi.nlm.nih.gov/pubmed/35721517 http://dx.doi.org/10.3389/fcell.2022.875132

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