Evolved resistance to a novel cationic peptide antibiotic requires high mutation supply

BACKGROUND AND OBJECTIVES: A key strategy for resolving the antibiotic resistance crisis is the development of new drugs with antimicrobial properties. The engineered cationic antimicrobial peptide WLBU2 (also known as PLG0206) is a promising broad-spectrum antimicrobial compound that has completed...

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Detalles Bibliográficos
Autores principales: Santos-Lopez, Alfonso, Fritz, Melissa J, Lombardo, Jeffrey B, Burr, Ansen H P, Heinrich, Victoria A, Marshall, Christopher W, Cooper, Vaughn S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198447/
https://www.ncbi.nlm.nih.gov/pubmed/35712084
http://dx.doi.org/10.1093/emph/eoac022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198447/
https://www.ncbi.nlm.nih.gov/pubmed/35712084
http://dx.doi.org/10.1093/emph/eoac022

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