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Evolved resistance to a novel cationic peptide antibiotic requires high mutation supply
BACKGROUND AND OBJECTIVES: A key strategy for resolving the antibiotic resistance crisis is the development of new drugs with antimicrobial properties. The engineered cationic antimicrobial peptide WLBU2 (also known as PLG0206) is a promising broad-spectrum antimicrobial compound that has completed...
Autores principales: | Santos-Lopez, Alfonso, Fritz, Melissa J, Lombardo, Jeffrey B, Burr, Ansen H P, Heinrich, Victoria A, Marshall, Christopher W, Cooper, Vaughn S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198447/ https://www.ncbi.nlm.nih.gov/pubmed/35712084 http://dx.doi.org/10.1093/emph/eoac022 |
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