FKBP51 mediates resilience to inflammation-induced anxiety through regulation of glutamic acid decarboxylase 65 expression in mouse hippocampus

BACKGROUND: Inflammation is a potential risk factor of mental disturbance. FKBP5 that encodes FK506-binding protein 51 (FKBP51), a negative cochaperone of glucocorticoid receptor (GR), is a stress-inducible gene and has been linked to psychiatric disorders. Yet, the role of FKBP51 in the inflammator...

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Detalles Bibliográficos
Autores principales: Gan, Yu-Ling, Wang, Chen-Yu, He, Rong-Heng, Hsu, Pei-Chien, Yeh, Hsin-Hsien, Hsieh, Tsung-Han, Lin, Hui-Ching, Cheng, Ming-Yen, Jeng, Chung-Jiuan, Huang, Ming-Chyi, Lee, Yi-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198626/
https://www.ncbi.nlm.nih.gov/pubmed/35705957
http://dx.doi.org/10.1186/s12974-022-02517-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198626/
https://www.ncbi.nlm.nih.gov/pubmed/35705957
http://dx.doi.org/10.1186/s12974-022-02517-8

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