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Selective Sphingosine 1-Phosphate Receptor 1 Modulation Augments Thrombolysis of Low-Dose Tissue Plasminogen Activator Following Cerebrovascular Thrombosis

BACKGROUND: Results from our recent study demonstrate that sphingosine-1-phosphate receptor 1 (S1PR1) modulation improves microvascular hemodynamics after cerebrovascular thrombosis. This study was to determine the microvascular hemodynamic effects of a sub-thrombolytic dose of tPA combined with a s...

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Detalles Bibliográficos
Autores principales: Li, Han-Dong, Li, Ran, Kong, Ying, Zhang, Wenyan, Qi, Caiyun, Wang, Dan, Hao, Hongying, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198651/
https://www.ncbi.nlm.nih.gov/pubmed/35720286
http://dx.doi.org/10.3389/fimmu.2022.801727