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Heightened Tameness and Accelerated Handling-Habituation in 3×Tg-AD Mice on a B6;129 Genetic Background

BACKGROUND: The triple transgenic mouse model of Alzheimer’s disease (3×Tg-AD) has gained popularity in Alzheimer’s research owing to the progressive development of both amyloid-β and tau pathologies in its brain. Prior handling-habituation, a necessary preparation procedure that reduces anxiety and...

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Detalles Bibliográficos
Autores principales: Hu, Wen, Dai, Chun-Ling, Niu, Jiahui, Iqbal, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198767/
https://www.ncbi.nlm.nih.gov/pubmed/35719714
http://dx.doi.org/10.3233/ADR-220007