Association Between the Cholinesterase Inhibitor Donepezil and the Cholinergic Precursor Choline Alphoscerate in the Treatment of Depression in Patients with Alzheimer’s Disease

BACKGROUND: Depressive symptoms are common in Alzheimer’s disease (AD) patients and are associated with an increased functional decline. Selective serotonin reuptake inhibitor antidepressants showed a limited efficacy. OBJECTIVE: The purpose of this work was to evaluate if a higher brain cholinergic...

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Detalles Bibliográficos
Autores principales: Carotenuto, Anna, Fasanaro, Angiola Maria, Manzo, Valentino, Amenta, Francesco, Traini, Enea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198805/
https://www.ncbi.nlm.nih.gov/pubmed/35719710
http://dx.doi.org/10.3233/ADR-200269