A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe prothrombotic complication of adenoviral vaccines, including the ChAdOx1 nCoV-19 (Vaxzevria) vaccine. The putative mechanism involves formation of pathological anti–platelet factor 4 (PF4) antibodies that activate platelets via th...

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Detalles Bibliográficos
Autores principales: Lee, Christine S.M., Liang, Hai Po Helena, Connor, David E., Dey, Agnibesh, Tohidi-Esfahani, Ibrahim, Campbell, Heather, Whittaker, Shane, Capraro, David, Favaloro, Emmanuel J., Donikian, Dea, Kondo, Mayuko, Hicks, Sarah M., Choi, Philip Y.-I., Gardiner, Elizabeth E., Clarke, Lisa Joanne, Tran, Huyen, Passam, Freda H., Brighton, Timothy Andrew, Chen, Vivien M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198924/
https://www.ncbi.nlm.nih.gov/pubmed/35359002
http://dx.doi.org/10.1182/bloodadvances.2021006698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198924/
https://www.ncbi.nlm.nih.gov/pubmed/35359002
http://dx.doi.org/10.1182/bloodadvances.2021006698

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