Targeting hypersialylation in multiple myeloma represents a novel approach to enhance NK cell–mediated tumor responses

Abnormal glycosylation is a hallmark of cancer, and the hypersialylated tumor cell surface facilitates abnormal cell trafficking and drug resistance in several malignancies, including multiple myeloma (MM). Furthermore, hypersialylation has also been implicated in facilitating evasion of natural kil...

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Detalles Bibliográficos
Autores principales: Daly, John, Sarkar, Subhashis, Natoni, Alessandro, Stark, Jessica C., Riley, Nicholas M., Bertozzi, Carolyn R., Carlsten, Mattias, O'Dwyer, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198929/
https://www.ncbi.nlm.nih.gov/pubmed/35294519
http://dx.doi.org/10.1182/bloodadvances.2021006805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198929/
https://www.ncbi.nlm.nih.gov/pubmed/35294519
http://dx.doi.org/10.1182/bloodadvances.2021006805

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