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Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells

Polycythemia vera (PV) is a stem cell disorder characterized by hyperproliferation of the myeloid lineages and the presence of an activating JAK2 mutation. To elucidate mechanisms controlling PV stem and progenitor cell biology, we applied a recently developed highly sensitive data-independent acqui...

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Detalles Bibliográficos
Autores principales: Tan, Ge, Wolski, Witold E., Kummer, Sandra, Hofstetter, Mara, Theocharides, Alexandre P. A., Manz, Markus G., Aebersold, Ruedi, Meier-Abt, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198936/
https://www.ncbi.nlm.nih.gov/pubmed/35008095
http://dx.doi.org/10.1182/bloodadvances.2021005344