Clinical activity of single-dose systemic oncolytic VSV virotherapy in patients with relapsed refractory T-cell lymphoma

Clinical success with intravenous (IV) oncolytic virotherapy (OV) has to-date been anecdotal. We conducted a phase 1 clinical trial of systemic OV and investigated the mechanisms of action in responding patients. A single IV dose of vesicular stomatitis virus (VSV) interferon-β (IFN-β) with sodium i...

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Detalles Bibliográficos
Autores principales: Cook, Joselle, Peng, Kah-Whye, Witzig, Thomas E., Broski, Stephen M., Villasboas, Jose C., Paludo, Jonas, Patnaik, Mrinal, Rajkumar, Vincent, Dispenzieri, Angela, Leung, Nelson, Buadi, Francis, Bennani, Nora, Ansell, Stephen M., Zhang, Lianwen, Packiriswamy, Nandakumar, Balakrishnan, Baskar, Brunton, Bethany, Giers, Marissa, Ginos, Brenda, Dueck, Amylou C., Geyer, Susan, Gertz, Morie A., Warsame, Rahma, Go, Ronald S., Hayman, Suzanne R., Dingli, David, Kumar, Shaji, Bergsagel, Leif, Munoz, Javier L., Gonsalves, Wilson, Kourelis, Taxiarchis, Muchtar, Eli, Kapoor, Prashant, Kyle, Robert A., Lin, Yi, Siddiqui, Mustaqeem, Fonder, Amie, Hobbs, Miriam, Hwa, Lisa, Naik, Shruthi, Russell, Stephen J., Lacy, Martha Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Clinical Trials and Observations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198941/
https://www.ncbi.nlm.nih.gov/pubmed/35175355
http://dx.doi.org/10.1182/bloodadvances.2021006631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198941/
https://www.ncbi.nlm.nih.gov/pubmed/35175355
http://dx.doi.org/10.1182/bloodadvances.2021006631

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