Assessment of iron overload in a cohort of Sri Lankan patients with transfusion dependent beta thalassaemia and its correlation with pathogenic variants in HBB, HFE, SLC40A1, and TFR2 genes

BACKGROUND: Iron overload (IO) is a complication in transfusion dependent beta thalassaemia (TDT). Pathogenic variants in genes involving iron metabolism may confer increased risk of IO. The objective of this study was to determine the magnitude of the cardiac and hepatic IO and determine whether pa...

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Detalles Bibliográficos
Autores principales: Dissanayake, Ruwangi, Samarasinghe, Nayana, Waidyanatha, Samantha, Pathirana, Sajeewani, Neththikumara, Nilaksha, Dissanayake, Vajira H. W., Wetthasinghe, Kalum, Gooneratne, Lallindra, Wickramasinghe, Pujitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199146/
https://www.ncbi.nlm.nih.gov/pubmed/35705926
http://dx.doi.org/10.1186/s12887-022-03191-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199146/
https://www.ncbi.nlm.nih.gov/pubmed/35705926
http://dx.doi.org/10.1186/s12887-022-03191-8

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