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Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice

Parkinson’s disease, the second most common neurodegenerative disorder, is characterized by the loss of nigrostriatal dopamine neurons. FBXO7 (F-box protein only 7) (PARK15) mutations cause early-onset Parkinson’s disease. FBXO7 is a subunit of the SCF (SKP1/cullin-1/F-box protein) E3 ubiquitin liga...

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Detalles Bibliográficos
Autores principales:	Noda, Sachiko, Sato, Shigeto, Fukuda, Takahiro, Ueno, Shinichi, Tada, Norihiro, Hattori, Nobutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Micro Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199167/ https://www.ncbi.nlm.nih.gov/pubmed/35701754 http://dx.doi.org/10.1186/s13041-022-00936-5

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