SCADIE: simultaneous estimation of cell type proportions and cell type-specific gene expressions using SCAD-based iterative estimating procedure

A challenge in bulk gene differential expression analysis is to differentiate changes due to cell type-specific gene expression and cell type proportions. SCADIE is an iterative algorithm that simultaneously estimates cell type-specific gene expression profiles and cell type proportions, and perform...

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Detalles Bibliográficos
Autores principales: Tang, Daiwei, Park, Seyoung, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199219/
https://www.ncbi.nlm.nih.gov/pubmed/35706040
http://dx.doi.org/10.1186/s13059-022-02688-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199219/
https://www.ncbi.nlm.nih.gov/pubmed/35706040
http://dx.doi.org/10.1186/s13059-022-02688-w

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