DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction

BACKGROUND: Tight junctions (TJ) are multi-protein complexes that hold epithelial cells together and form structural and functional barriers for maintaining proper biological activities. Dual specificity phosphatase 3 (DUSP3), a suppressor of multiple protein tyrosine (Tyr) kinases, is decreased in...

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Detalles Bibliográficos
Autores principales: Chou, Hsiao-Chin, Cheng, Chun-Mei, Yang, Chi-Hwa, Lin, Tzu-Yin, Liu, Ya-Wen, Tan, Tse-Hua, Chen, Yi-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199239/
https://www.ncbi.nlm.nih.gov/pubmed/35705979
http://dx.doi.org/10.1186/s12929-022-00826-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199239/
https://www.ncbi.nlm.nih.gov/pubmed/35705979
http://dx.doi.org/10.1186/s12929-022-00826-x

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