Iguratimod Restrains Circulating Follicular Helper T Cell Function by Inhibiting Glucose Metabolism via Hif1α-HK2 Axis in Rheumatoid Arthritis

Iguratimod (IGU) is a novel disease modified anti-rheumatic drug, which has been found to act directly on B cells for inhibiting the production of antibodies in rheumatoid arthritis (RA) patients. Follicular helper T (Tfh) cells, a key T cell subsets in supporting B cell differentiation and antibody...

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Detalles Bibliográficos
Autores principales: Bai, Ziran, Lu, Zhimin, Liu, Rui, Tang, Yawei, Ye, Xiaokang, Jin, Minli, Wang, Guan, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199372/
https://www.ncbi.nlm.nih.gov/pubmed/35720293
http://dx.doi.org/10.3389/fimmu.2022.757616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199372/
https://www.ncbi.nlm.nih.gov/pubmed/35720293
http://dx.doi.org/10.3389/fimmu.2022.757616

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