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Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis

The lung alveolus is lined with alveolar type 1 (AT1) and type 2 (AT2) epithelial cells. During alveologenesis, increasing demand associated with expanding alveolar numbers is met by proliferating progenitor AT2s (pAT2). Little information exists regarding the identity of this population and their n...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Li, Changgong, Danopoulos, Soula, Al Alam, Denise, Peinado, Neil, Webster, Sha, Borok, Zea, Kohbodi, GoleNaz Adeli, Bellusci, Saverio, Minoo, Parviz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199394/
https://www.ncbi.nlm.nih.gov/pubmed/35385750
http://dx.doi.org/10.1016/j.celrep.2022.110608