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Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis
The lung alveolus is lined with alveolar type 1 (AT1) and type 2 (AT2) epithelial cells. During alveologenesis, increasing demand associated with expanding alveolar numbers is met by proliferating progenitor AT2s (pAT2). Little information exists regarding the identity of this population and their n...
Autores principales: | Gao, Feng, Li, Changgong, Danopoulos, Soula, Al Alam, Denise, Peinado, Neil, Webster, Sha, Borok, Zea, Kohbodi, GoleNaz Adeli, Bellusci, Saverio, Minoo, Parviz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199394/ https://www.ncbi.nlm.nih.gov/pubmed/35385750 http://dx.doi.org/10.1016/j.celrep.2022.110608 |
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