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Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells

Chinese hamster ovary (CHO) cells are currently the most widely used host cells for recombinant therapeutic protein (RTP) production. Currently, the RTP yields need to increase further to meet the market needs and reduce costs. In this study, three stabilizing and anti-repressor (SAR) elements from...

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Detalles Bibliográficos
Autores principales: Li, Qin, Yan, Rui-Fang, Yang, Yong-Xiao, Mi, Chun-liu, Jia, Yan-long, Wang, Tian-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199445/
https://www.ncbi.nlm.nih.gov/pubmed/35721852
http://dx.doi.org/10.3389/fbioe.2022.840600