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Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells
Chinese hamster ovary (CHO) cells are currently the most widely used host cells for recombinant therapeutic protein (RTP) production. Currently, the RTP yields need to increase further to meet the market needs and reduce costs. In this study, three stabilizing and anti-repressor (SAR) elements from...
Autores principales: | Li, Qin, Yan, Rui-Fang, Yang, Yong-Xiao, Mi, Chun-liu, Jia, Yan-long, Wang, Tian-Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199445/ https://www.ncbi.nlm.nih.gov/pubmed/35721852 http://dx.doi.org/10.3389/fbioe.2022.840600 |
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