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S-Nitroso-L-Cysteine Stereoselectively Blunts the Deleterious Effects of Fentanyl on Breathing While Augmenting Antinociception in Freely-Moving Rats

Endogenous and exogenously administered S-nitrosothiols modulate the activities of central and peripheral systems that control breathing. We have unpublished data showing that the deleterious effects of morphine on arterial blood-gas chemistry (i.e., pH, pCO(2), pO(2), and sO(2)) and Alveolar-arteri...

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Detalles Bibliográficos
Autores principales: Getsy, Paulina M., Baby, Santhosh M., Gruber, Ryan B., Gaston, Benjamin, Lewis, Tristan H. J., Grossfield, Alan, Seckler, James M., Hsieh, Yee-Hsee, Bates, James N., Lewis, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199495/
https://www.ncbi.nlm.nih.gov/pubmed/35721204
http://dx.doi.org/10.3389/fphar.2022.892307