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Post-Translational Modifications of BACE1 in Alzheimer's Disease

Beta-Amyloid Cleaving Enzyme1 (BACE1) is a monospecific enzyme for the key rate-limiting step in the synthesis of beta-amyloid(Aβ) from cleavage of amyloid precursor protein (APP), to form senile plaques and causes cognitive dysfunction in Alzheimer's disease (AD). Post-translation modification...

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Detalles Bibliográficos
Autores principales: Wen, Wen, Li, Ping, Liu, Panwang, Xu, Shijun, Wang, Fushun, Huang, Jason H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199555/
https://www.ncbi.nlm.nih.gov/pubmed/33475074
http://dx.doi.org/10.2174/1570159X19666210121163224