Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers

Tirabrutinib (TIRA), a potent and nonreversible oral Bruton tyrosine kinase inhibitor, is evaluated for treatment of certain hematological malignancies and inflammatory diseases. A drug–drug interaction study to evaluate the effect of TIRA on the pharmacokinetics of the oral contraceptive levonorges...

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Detalles Bibliográficos
Autores principales: Cherala, Ganesh, Nelson, Cara, Guo, Ying, Mathur, Anubhav, Tarnowski, Thomas, Othman, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199868/
https://www.ncbi.nlm.nih.gov/pubmed/35266297
http://dx.doi.org/10.1111/cts.13265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199868/
https://www.ncbi.nlm.nih.gov/pubmed/35266297
http://dx.doi.org/10.1111/cts.13265

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