Cargando…

Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers

Tirabrutinib (TIRA), a potent and nonreversible oral Bruton tyrosine kinase inhibitor, is evaluated for treatment of certain hematological malignancies and inflammatory diseases. A drug–drug interaction study to evaluate the effect of TIRA on the pharmacokinetics of the oral contraceptive levonorges...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cherala, Ganesh, Nelson, Cara, Guo, Ying, Mathur, Anubhav, Tarnowski, Thomas, Othman, Ahmed A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199868/ https://www.ncbi.nlm.nih.gov/pubmed/35266297 http://dx.doi.org/10.1111/cts.13265

Ejemplares similares

Atogepant Has No Clinically Relevant Effects on the Pharmacokinetics of an Ethinyl Estradiol/Levonorgestrel Oral Contraceptive in Healthy Female Participants
por: Ankrom, Wendy, et al.
Publicado: (2020)

551. MK-8591 Does Not Alter the Pharmacokinetics of the Oral Contraceptives Ethinyl Estradiol and Levonorgestrel
por: Ankrom, Wendy, et al.
Publicado: (2018)

The New Extended-Cycle Levonorgestrel-Ethinyl Estradiol Oral Contraceptives
por: Bonnema, Rachel A., et al.
Publicado: (2011)

New low-dose, extended-cycle pills with levonorgestrel and ethinyl estradiol: an evolutionary step in birth control
por: Nelson, Anita
Publicado: (2010)

Cycle control with an extended-regimen oral contraceptive combining levonorgestrel and ethinyl estradiol that includes continuous low-dose ethinyl estradiol instead of the traditional hormone-free interval
por: Nappi, Rossella E, et al.
Publicado: (2017)

The lowest-dose, extended-cycle combined oral contraceptive pill with continuous ethinyl estradiol in the United States: a review of the literature on ethinyl estradiol 20 μg/levonorgestrel 100 μg + ethinyl estradiol 10 μg
por: Krishnan, Sheila, et al.
Publicado: (2010)

No Interacting Influence of Lavender Oil Preparation Silexan on Oral Contraception Using an Ethinyl Estradiol/Levonorgestrel Combination
por: Heger-Mahn, Doris, et al.
Publicado: (2014)

Extended regimen of a levonorgestrel/ethinyl estradiol transdermal delivery system: Predicted serum hormone levels using a population pharmacokinetic model
por: Stanczyk, Frank Z., et al.
Publicado: (2022)

High-sensitivity simultaneous liquid chromatography–tandem mass spectrometry assay of ethinyl estradiol and levonorgestrel in human plasma()
por: Gandhi, Abhishek, et al.
Publicado: (2015)

Lack of effect of oral cabotegravir on the pharmacokinetics of a levonorgestrel/ethinyl oestradiol‐containing oral contraceptive in healthy adult women
por: Trezza, Christine, et al.
Publicado: (2017)

A phase 1, open‐label study to evaluate the drug interaction between islatravir (MK‐8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females
por: Ankrom, Wendy, et al.
Publicado: (2021)

Dolutegravir Has No Effect on the Pharmacokinetics of Oral Contraceptives With Norgestimate and Ethinyl Estradiol
por: Song, Ivy H., et al.
Publicado: (2015)

Experimental Hepatotoxicity Produced by Ethinyl estradiol
por: Pandey, Govind, et al.
Publicado: (2011)

Determination of Ethinyl Estradiol and Levonorgestrel in Human Plasma with Prednisone as Internal Standard Using Ultra-performance Liquid Chromatography–Tandem Mass Spectrometry
por: Harahap, Yahdiana, et al.
Publicado: (2019)

Impacts of Bisphenol A and Ethinyl Estradiol on Male and Female CD-1 Mouse Spleen
por: Gear, Robin B., et al.
Publicado: (2017)

The JAK1 Inhibitor Upadacitinib Has No Effect on the Pharmacokinetics of Levonorgestrel and Ethinylestradiol: A Study in Healthy Female Subjects
por: Mohamed, Mohamed‐Eslam F., et al.
Publicado: (2018)

The comparison of the effectiveness and safety of drospirone ethinyl estradiol and ethinyl estradiol cyproterone in the treatment of polycystic ovarian syndrome: A protocol for systematic review and meta-analysis
por: Liu, Zhimin, et al.
Publicado: (2020)

Investigation of the Hemostatic Effect of a Transdermal Patch Containing 0.55 mg Ethinyl Estradiol and 2.1 mg Gestodene Compared with a Monophasic Oral Contraceptive Containing 0.03 mg Ethinyl Estradiol and 0.15 mg Levonorgestrel: An Open-Label, Randomized, Crossover Study
por: Junge, Wolfgang, et al.
Publicado: (2013)

The Uptake of Ethinyl-Estradiol and Cortisol From Water by Mussels (Mytilus spp.)
por: Katsiadaki, Ioanna, et al.
Publicado: (2021)

Pharmacokinetic Interaction Between the MEK1/MEK2 Inhibitor Trametinib and Oral Contraceptives Containing Norethindrone and Ethinyl Estradiol in Female Patients With Solid Tumors
por: Arkenau, Hendrik‐Tobias, et al.
Publicado: (2022)

Assessment of the Effect of Filgotinib on the Pharmacokinetics of Atorvastatin, Pravastatin, and Rosuvastatin in Healthy Adult Participants
por: Anderson, Kacey, et al.
Publicado: (2021)

Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults
por: Townsend, Robert, et al.
Publicado: (2016)

Neonatal Exposure to 17α-Ethinyl Estradiol Affects Kisspeptin Expression and LH-Surge Level in Female Rats
por: USUDA, Kento, et al.
Publicado: (2014)

Estradiol/levonorgestrel: Pulmonary thromboembolism: case report
Publicado: (2022)

Efficacy and safety of combined ethinyl estradiol/drospirenone oral contraceptives in the treatment of acne
por: Tan, Jerry KL, et al.
Publicado: (2010)

Rapid Screening Method for Detecting Ethinyl Estradiol in Natural Water Employing Voltammetry
por: Nunes, Chalder Nogueira, et al.
Publicado: (2016)

Portal Venous Thrombosis Associated with Use of Etonogestrel/ethinyl Estradiol Vaginal Ring
por: Bailey, Katelynn E., et al.
Publicado: (2020)

Pharmacokinetic overview of ethinyl estradiol dose and bioavailability using two transdermal contraceptive systems and a standard combined oral contraceptive
por: Hofmann, Birte, et al.
Publicado: (2014)

Hypothalamic transcriptomic alterations in male and female California mice (Peromyscus californicus) developmentally exposed to bisphenol A or ethinyl estradiol
por: Johnson, Sarah A., et al.
Publicado: (2017)

Treatment of premenstrual dysphoric disorder (PMDD) with a novel formulation of drospirenone and ethinyl estradiol
por: De Berardis, Domenico, et al.
Publicado: (2007)

The Primodos components Norethisterone acetate and Ethinyl estradiol induce developmental abnormalities in zebrafish embryos
por: Brown, Samantha, et al.
Publicado: (2018)

Semi‐Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA
por: Meng, Amy, et al.
Publicado: (2021)

Unilateral Erythema Nodosum following Norethindrone Acetate, Ethinyl Estradiol, and Ferrous Fumarate Combination Therapy
por: Min, Michelle S., et al.
Publicado: (2016)

3,2′‐Dimethyl‐4‐aminobiphenyl‐induced Gallbladder Carcinogenesis and Effects of Ethinyl Estradiol in Hamsters
por: Hasegawa, Ryohei, et al.
Publicado: (1992)

Cerebral Sinus Venous Thrombosis in a Patient Using Etonogestrel/Ethinyl Estradiol Vaginal Ring
por: Selim, Mohammad, et al.
Publicado: (2018)

Oral ethinyl estradiol treatment in women with cystic fibrosis is associated with lower bone mineral density
por: Wu, Malinda, et al.
Publicado: (2020)

Data describing lack of effects of 17α-ethinyl estradiol on mammary gland morphology in female mice exposed during pregnancy and lactation
por: LaPlante, Charlotte D., et al.
Publicado: (2017)

Simultaneous Degradation of Estrone, 17β-Estradiol and 17α-Ethinyl Estradiol in an Aqueous UV/H(2)O(2) System
por: Ma, Xiaoyan, et al.
Publicado: (2015)

Double Dosing Levonorgestrel-Based Emergency Contraception for Individuals With Obesity: A Randomized Controlled Trial
por: Edelman, Alison B., et al.
Publicado: (2022)

GPR30, but not estrogen receptor-α, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol
por: Yates, Melissa A, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_m2q44pvce7ktic9bjqf3qb84ai