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Strategic, feasibility, economic, and cultural aspects of phase 0 approaches: Is it time to change the drug development process in order to increase productivity?

Research conducted over the past 2 decades has enhanced the validity and expanded the applications of microdosing and other phase 0 approaches in drug development. Phase 0 approaches can accelerate drug development timelines and reduce attrition in clinical development by increasing the quality of c...

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Detalles Bibliográficos
Autores principales: Burt, Tal, Roffel, Ad F., Langer, Oliver, Anderson, Kirsten, DiMasi, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199889/
https://www.ncbi.nlm.nih.gov/pubmed/35278281
http://dx.doi.org/10.1111/cts.13269