Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6‐hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots

The suitability of the endogenous 6‐hydroxymelatonin/melatonin urinary metabolic ratio as a surrogate for the paraxanthine/caffeine ratio to predict cytochrome P450 1A2 (CYP1A2) activity was assessed in this study. Twelve healthy volunteers completed four study sessions spread over 1 month (includin...

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Detalles Bibliográficos
Autores principales: Magliocco, Gaëlle, Desmeules, Jules, Samer, Caroline Flora, Thomas, Aurélien, Daali, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199893/
https://www.ncbi.nlm.nih.gov/pubmed/35338582
http://dx.doi.org/10.1111/cts.13263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199893/
https://www.ncbi.nlm.nih.gov/pubmed/35338582
http://dx.doi.org/10.1111/cts.13263

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