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Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6‐hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots

The suitability of the endogenous 6‐hydroxymelatonin/melatonin urinary metabolic ratio as a surrogate for the paraxanthine/caffeine ratio to predict cytochrome P450 1A2 (CYP1A2) activity was assessed in this study. Twelve healthy volunteers completed four study sessions spread over 1 month (includin...

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Detalles Bibliográficos
Autores principales:	Magliocco, Gaëlle, Desmeules, Jules, Samer, Caroline Flora, Thomas, Aurélien, Daali, Youssef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199893/ https://www.ncbi.nlm.nih.gov/pubmed/35338582 http://dx.doi.org/10.1111/cts.13263

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