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PGC-1α-Mediated Mitochondrial Quality Control: Molecular Mechanisms and Implications for Heart Failure

Mitochondria with structural and functional integrity are essential for maintaining mitochondrial function and cardiac homeostasis. It is involved in the pathogenesis of many diseases. Peroxisome proliferator-activated receptor γ coactivator 1 α (PGC-1α), acted as a transcriptional cofactor, is abun...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Qin, Yuan, Liu, Bilin, Gao, Meng, Li, Anqi, Li, Xue, Gong, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199988/
https://www.ncbi.nlm.nih.gov/pubmed/35721484
http://dx.doi.org/10.3389/fcell.2022.871357