Cargando…

PGC-1α-Mediated Mitochondrial Quality Control: Molecular Mechanisms and Implications for Heart Failure

Mitochondria with structural and functional integrity are essential for maintaining mitochondrial function and cardiac homeostasis. It is involved in the pathogenesis of many diseases. Peroxisome proliferator-activated receptor γ coactivator 1 α (PGC-1α), acted as a transcriptional cofactor, is abun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Lei, Qin, Yuan, Liu, Bilin, Gao, Meng, Li, Anqi, Li, Xue, Gong, Guohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199988/ https://www.ncbi.nlm.nih.gov/pubmed/35721484 http://dx.doi.org/10.3389/fcell.2022.871357

Ejemplares similares

Mitochondrial Dynamics in Adult Cardiomyocytes and Heart Diseases
por: Li, Anqi, et al.
Publicado: (2020)

Distinct Roles of Zmynd17 and PGC1α in Mitochondrial Quality Control and Biogenesis in Skeletal Muscle
por: Yoshioka, Kiyoshi, et al.
Publicado: (2019)

Mitochondrial Fusion Protein Mfn2 and Its Role in Heart Failure
por: Chen, Lei, et al.
Publicado: (2021)

Dihydromyricetin Protects Against Gentamicin-Induced Ototoxicity via PGC-1α/SIRT3 Signaling in vitro
por: Han, Hezhou, et al.
Publicado: (2020)

Editorial: Mitochondrial control of cell fate
por: Gong, Guohua, et al.
Publicado: (2023)

DNA Methylation of PGC-1α Is Associated With Elevated mtDNA Copy Number and Altered Urinary Metabolites in Autism Spectrum Disorder
por: Bam, Sophia, et al.
Publicado: (2021)

mtDNA Heteroplasmy at the Core of Aging-Associated Heart Failure. An Integrative View of OXPHOS and Mitochondrial Life Cycle in Cardiac Mitochondrial Physiology
por: Elorza, Alvaro A., et al.
Publicado: (2021)

Zebrafish Heart Failure Models
por: Narumanchi, Suneeta, et al.
Publicado: (2021)

Mitochondrial autophagy: molecular mechanisms and implications for cardiovascular disease
por: Li, Anqi, et al.
Publicado: (2022)

RNA-Binding Proteins Implicated in Mitochondrial Damage and Mitophagy
por: Ravanidis, Stylianos, et al.
Publicado: (2020)

Microbiota-Derived Metabolite Trimethylamine N-Oxide Protects Mitochondrial Energy Metabolism and Cardiac Functionality in a Rat Model of Right Ventricle Heart Failure
por: Videja, Melita, et al.
Publicado: (2021)

Modified Protocol for A Mouse Heart Failure Model Using Minimally Invasive Transverse Aortic Constriction
por: Liu, Bilin, et al.
Publicado: (2020)

AMPKα2 Overexpression Reduces Cardiomyocyte Ischemia-Reperfusion Injury Through Normalization of Mitochondrial Dynamics
por: Deng, Yuanyan, et al.
Publicado: (2020)

Regulation of Mitochondrial Quality Control by Natural Drugs in the Treatment of Cardiovascular Diseases: Potential and Advantages
por: Chang, Xing, et al.
Publicado: (2020)

Reduction of Drosophila Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia
por: Saoji, Maithili, et al.
Publicado: (2022)

Dynamic Mitochondrial Proteome Under Polyamines Treatment in Cardiac Aging
por: Zhang, Hao, et al.
Publicado: (2022)

Single-Cell RNA Sequencing and Quantitative Proteomics Analysis Elucidate Marker Genes and Molecular Mechanisms in Hypoplastic Left Heart Patients With Heart Failure
por: Ma, Li, et al.
Publicado: (2021)

Tubulin Post-translational Modifications: Potential Therapeutic Approaches to Heart Failure
por: Liu, Chang, et al.
Publicado: (2022)

Mitochondrial Ca(2 +) Is Related to Mitochondrial Activity and Dynamic Events in Mouse Oocytes
por: Wang, Feng, et al.
Publicado: (2020)

Fas-Activated Serine/Threonine Kinase Governs Cardiac Mitochondrial Complex I Functional Integrity in Ischemia/Reperfusion Heart
por: Chen, Xiyao, et al.
Publicado: (2021)

Mitochondrial Quality Control Governed by Ubiquitin
por: Ravanelli, Sonia, et al.
Publicado: (2020)

Protein Quality Control at the Mitochondrial Surface
por: den Brave, Fabian, et al.
Publicado: (2021)

Targeting Orai1-Mediated Store-Operated Ca(2+) Entry in Heart Failure
por: Luo, Rui, et al.
Publicado: (2020)

PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity
por: Iacovelli, Jared, et al.
Publicado: (2016)

Loss of cholinergic receptor muscarinic 1 impairs cortical mitochondrial structure and function: implications in Alzheimer’s disease
por: Sabbir, Mohammad Golam, et al.
Publicado: (2023)

Hexestrol Deteriorates Oocyte Quality via Perturbation of Mitochondrial Dynamics and Function
por: Niu, Dong, et al.
Publicado: (2021)

Exploring key genes associated with neutrophil function and neutrophil extracellular traps in heart failure: a comprehensive analysis of single-cell and bulk sequencing data
por: Li, Xudong, et al.
Publicado: (2023)

Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in dilated cardiomyopathy with heart failure
por: Zhu, Yihao, et al.
Publicado: (2022)

Cardiac Mesenchymal Cells Cultured at Physiologic Oxygen Tension Have Superior Therapeutic Efficacy in Heart Failure Caused by Myocardial Infarction
por: Bolli, Robi A. R., et al.
Publicado: (2021)

Quality Matters? The Involvement of Mitochondrial Quality Control in Cardiovascular Disease
por: Lin, Kai-Lieh, et al.
Publicado: (2021)

Mitochondrial quality control in health and cardiovascular diseases
por: Atici, Asli E., et al.
Publicado: (2023)

A Novel Assisted Oocyte Activation Method Improves Fertilization in Patients With Recurrent Fertilization Failure
por: Wang, Meng, et al.
Publicado: (2021)

Genetic and Functional Characterization of Novel Brown-Like Adipocytes Around the Lamprey Brain
por: Xu, XiaoLuan, et al.
Publicado: (2021)

Expression of Concern: AMPKα2 overexpression reduces cardiomyocyte ischemia-reperfusion injury through normalization of mitochondrial dynamics
Publicado: (2022)

Age and Mutations as Predictors of the Response to Immunotherapy in Head and Neck Squamous Cell Cancer
por: Zhang, Yueming, et al.
Publicado: (2020)

Mitochondrial Ca(2+) Overload Leads to Mitochondrial Oxidative Stress and Delayed Meiotic Resumption in Mouse Oocytes
por: Zhang, Luyao, et al.
Publicado: (2020)

Corrigendum: A novel assisted oocyte activation method improves fertilization in patients with recurrent fertilization failure
por: Wang, Meng, et al.
Publicado: (2023)

TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression
por: Xie, Chunfeng, et al.
Publicado: (2021)

2-Hydroxy-Docosahexaenoic Acid Is Converted Into Heneicosapentaenoic Acid via α-Oxidation: Implications for Alzheimer’s Disease Therapy
por: Parets, Sebastià, et al.
Publicado: (2020)

The Loss of Mitochondrial Quality Control in Diabetic Kidney Disease
por: Dai, Wenni, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n0gang2odu6ofefs7d0ll9r9qh