HIF-1/2α-Activated RNF146 Enhances the Proliferation and Glycolysis of Hepatocellular Carcinoma Cells via the PTEN/AKT/mTOR Pathway

Hypoxia microenvironment, a critical feature of hepatocellular carcinoma, contributes to hepatocarcinogenesis, tumor progression and therapeutic resistance. Hypoxia-inducible factors (HIFs)-activated target genes are the main effectors in hypoxia-induced HCC progression. In this study, we identified...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Guoliang, Wang, Hao, Zhu, Ning, Lu, Qiliang, Liu, Junwei, Xu, Qiuran, Huang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200061/
https://www.ncbi.nlm.nih.gov/pubmed/35721496
http://dx.doi.org/10.3389/fcell.2022.893888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200061/
https://www.ncbi.nlm.nih.gov/pubmed/35721496
http://dx.doi.org/10.3389/fcell.2022.893888

Ejemplares similares