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HIF-1/2α-Activated RNF146 Enhances the Proliferation and Glycolysis of Hepatocellular Carcinoma Cells via the PTEN/AKT/mTOR Pathway

Hypoxia microenvironment, a critical feature of hepatocellular carcinoma, contributes to hepatocarcinogenesis, tumor progression and therapeutic resistance. Hypoxia-inducible factors (HIFs)-activated target genes are the main effectors in hypoxia-induced HCC progression. In this study, we identified...

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Detalles Bibliográficos
Autores principales:	Shen, Guoliang, Wang, Hao, Zhu, Ning, Lu, Qiliang, Liu, Junwei, Xu, Qiuran, Huang, Dongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200061/ https://www.ncbi.nlm.nih.gov/pubmed/35721496 http://dx.doi.org/10.3389/fcell.2022.893888

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