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Recombinant EGFL7 Mitigated Pressure Overload-Induced Cardiac Remodeling by Blocking PI3K [Formula: see text] /AKT/ [Formula: see text] Signaling in Macrophages

Inflammation and endothelial dysfunction play an essential role in heart failure (HF). Epidermal growth factor-like protein 7 (EGFL7) is upregulated during pathological hypoxia and exerts a protective role. However, it is unclear whether there is a link between abnormal EGFL7 expression and inflamma...

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Detalles Bibliográficos
Autores principales: Li, Lei, Zhao, Ying, Hu, Ying, Wang, Xiaohui, Jin, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200063/
https://www.ncbi.nlm.nih.gov/pubmed/35721105
http://dx.doi.org/10.3389/fphar.2022.858118