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Inducing and measuring apoptotic cell death in mouse pancreatic β-cells and in isolated islets

Type 2 diabetes is mediated by insulin resistance and pancreatic β-cell failure, the latter reflecting a combination of β-cell dysfunction, dedifferentiation, and apoptosis. Quantification of β-cell apoptosis in diabetes can be challenging both with respect to methodology and selection of clinically...

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Detalles Bibliográficos
Autores principales: McKimpson, Wendy M., Kitsis, Richard N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200107/
https://www.ncbi.nlm.nih.gov/pubmed/35719268
http://dx.doi.org/10.1016/j.xpro.2022.101287